DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2011; 136(22): 1172-1174DOI: 10.1055/s-0031-1280533 Hämatologie und Onkologie| CommentaryHämatologie© Georg Thieme Verlag KG Stuttgart · New YorkImmunthrombozytopenieImmune thrombocytopeniaA. Matzdorff1 1Onkologisches Zentrum Saarbrücken, Klinik für Hämatologie und Onkologie, Caritasklinik St. Theresia Recommend Article Abstract Buy Article Schlüsselwörter Immunthrombozytopenie - Thrombopoietin-Rezeptorantagonisten - Romiplostim - Rituximab - Splenektomie Keywords immune thrombocytopenia - thrombopoietin receptor agonists - romiplostim - rituximab - splenectomy Full Text References Literatur 1 Emmons R BV, Reid D M, Cohen R L. et al . Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction. Blood. 1996; 87 4068-4071 2 Godeau B, Porcher R, Fain O. et al . Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura – results of a prospective multicenter phase 2 study. Blood. 2008; 112 999-1004 3 Kuter D J. New thrombopoietic growth factors. Blood. 2007; 109 4607-4616 4 Kuter D J, Rummel M, Boccia R. et al . Romiplostim or standard of care in patients wtih immune thrombocytopenia. N Engl J Med. 2010; 363 1889-1899 5 Matzdorff A, Giagounidis A, Greinacher A. et al . Diagnostik und Therapie der Immunthrombozytopenie. Empfehlungen einer gemeinsamen Expertengruppe der DGHO, DGTI und GTH. Onkologie. 2010; 33 (Suppl 3) 2-20 6 Neunert C, Lim W, Crowther M, Cohen A, Solberg L, Crowther M. Clinical guideline update on „Immune Thrombocytopenia: an evidence based practice guideline developed by the American Society of Hematology”. Blood. 2011; e-pub ahead of print 7 Provan D, Stasi R, Newland A C. et al . International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010; 115 168-196 8 Rodeghiero F, Stasi R, Gernsheimer T. et al . Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura (ITP) of adults and children: Report from an International Working Group. Blood. 2009; 113 2386-2393 9 Zaja F, Baccarani M, Mazza P. et al . Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia. Blood. 2010; 115 2755-2762 Prof. Dr. med. A. Matzdorff Onkologisches Zentrum SaarbrückenKlinik für Hämatologie und OnkologieCaritasklinik St. Theresia Rheinstr. 2 66113 Saarbrücken Phone: 0681/406-1101 Fax: 0681/406-1103 Email: a.matzdorff@caritasklinik.de